After the sudden death of her husband, Simi, a young mother of three, makes the unexpected decision to drive his danfo bus to support her family. In a world that questions her place behind the wheel, she must navigate grief, financial strain, and the disapproval of family and community. Set against the vibrant backdrop of Lagos, 'God Knows Best' is a tender, powerful drama about a woman finding strength in the ordinary, defying expectations, and learning to carry loss without letting it define her.